The definition of pediatric obesity was incorrectly stated in the text of the report and in the Table footnote; however, the analysis was correct and used the CDC definition of pediatric obesity for children aged ≥2 years (body mass index [kg/m2] ≥95th percentile for age and sex based on CDC growth charts). MMWR and Morbidity and Mortality Weekly Report are service marks of the U.S. Department of Health and Human Services. * Number of children in each age group hospitalized with COVID-19 per 100,000 population. Saving Lives, Protecting People, https://www.cdc.gov/coronavirus/2019-ncov/covid-data/covidview/index.html, https://www.cdc.gov/coronavirus/2019-ncov/covid-data/covidview/purpose-methods.html, Centers for Disease Control and Prevention, U.S. Department of Health & Human Services, Multisystem inflammatory syndrome in children (MIS-C). This article is made freely available for use in accordance with BMJ's website terms and conditions for the duration of the covid-19 pandemic or until otherwise determined by BMJ. Hospital case fatality and emergence of variant of concern B.1.1.7, rapid CO-CIN report to NERVTAG and SAGE: unpublished analysis. Clin Infect Dis 2020;ciaa1012. * https://www.cdc.gov/coronavirus/2019-ncov/covid-data/covidview/index.html. The new UK variant of SARS-CoV-2 may be associated with an increased risk of death, emerging data are suggesting. These data will help to better define the clinical spectrum of disease in children and the contributions of race and ethnicity and underlying medical conditions to hospitalizations and outcomes. Hospitalization rates and characteristics of patients hospitalized with laboratory-confirmed coronavirus disease 2019—COVID-NET, 14 states, March 1–30, 2020. You may use, download and print the article for any lawful, non-commercial purpose (including text and data mining) provided that all copyright notices and trade marks are retained. Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website. Strong efficacy in Phase 3 UK trial with over 50% of cases attributable to the now-predominant UK variant and the remainder attributable to COVID-19 virus; Clinical efficacy demonstrated in Phase 2b South Africa trial with over 90% of sequenced cases attributable to prevalent South Africa escape variant The new UK variant of SARS-CoV-2 may be associated with an increased risk of death, emerging data are suggesting. § https://www.cdc.gov/coronavirus/2019-ncov/covid-data/covidview/purpose-methods.html. Paediatric mortality related to pandemic influenza A H1N1 infection in England: an observational population-based study. Gastrointestinal symptoms, including nausea or vomiting, abdominal pain, or diarrhea, were reported by 42% of hospitalized children overall. Please note: your email address is provided to the journal, which may use this information for marketing purposes. In a briefing paper published on 22 January the government’s New and Emerging Respiratory Virus Threats Advisory Group (NERVTAG) highlighted several preliminary analyses showing a possible increase in the severity of disease associated with the new variant of concern (VOC) B.1.1.7, which first emerged in Kent in September.1. . The analyses were all adjusted for age, location, time, and other variables. ¶ Rates are not shown among non-Hispanic Asian or Pacific Islanders and non-Hispanic American Indian/Alaska Natives because of small case counts, leading to unstable estimates. “Based on these analyses, there is a realistic possibility that infection with VOC B.1.1.7 is associated with an increased risk of death compared to infection with non-VOC viruses,” the briefing paper said. Centers for Disease Control and Prevention. and that’s where the work is needed.”, John Edmunds, professor in the Centre for the Mathematical Modelling of Infectious Diseases at the London School of Hygiene and Tropical Medicine and member of NERVTAG, said that, despite the uncertainty, he believed that the government “was right to raise it.”, “The evidence is pretty solid,” he told the briefing. ¶ Data are preliminary, and case counts and rates for recent hospital admissions are subject to lag. The cumulative COVID-19–associated hospitalization rate among children aged <18 years during the surveillance period was 8.0 per 100,000 and was highest among children aged <2 years (24.8); rates were substantially lower in children aged 2–4 years (4.2) and 5–17 years (6.4) (Figure 1). NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. ; Columbia Pediatric COVID-19 Management Group. Multisystem inflammatory syndrome in children in New York State. Collins JP, Campbell AP, Openo K, et al. and/or the original MMWR paper copy for printable versions of official text, figures, and tables. By comparison, among U.S. children hospitalized with seasonal influenza virus infection, estimates of ICU admissions have ranged from 16% to 25% among hospitalized children without and with underlying medical conditions, respectively, and reports of in-hospital deaths also are rare (<1%) (10). Proportion of asymptomatic coronavirus disease 2019 (COVID-19): a systematic review and meta-analysis. The latest results are an improvement from earlier findings. Hall, DVM1; Gayle E. Langley, MD1; Shikha Garg, MD1,2; COVID-NET Surveillance Team (View author affiliations). Both studies analysed cases of the new and old variant by linking community testing data with death data. Overall, Hispanic or Latino (Hispanic) and non-Hispanic black (black) children had higher cumulative rates of COVID-19–associated hospitalizations (16.4 and 10.5 per 100,000, respectively) than did non-Hispanic white (white) children (2.1). Among 67 children who had a chest radiograph during hospitalization, 44 (65.7%) radiographs showed an infiltrate or consolidation. “But what we have not been able to detect yet is an increased rate of hospitalisation, or once in hospital, an increased rate of dying with this variant versus another variant, so that’s where the uncertainty lies . Abbreviations: BIPAP = bilevel positive airway pressure; CT = computed tomography; CPAP = continuous positive airway pressure; COVID-19 = coronavirus disease 2019; COVID-NET = COVID-19–Associated Hospitalization Surveillance Network; ICU = intensive care unit; IQR = interquartile range; IVIG = intravenous immune globulin; N/A = not applicable; NH = non-Hispanic. start highlightThe most prevalent conditions included obesity (37.8%), chronic lung disease (18.0%), and prematurity (gestational age <37 weeks at birth, collected only for children aged <2 years) (15.4%)end highlight. William Schaffner reports personal fees from Pfizer and VBI Vaccines outside the submitted work. Lindsay Kim, MD1,2; Michael Whitaker, MPH1,3; Alissa O’Halloran, MSPH1; Anita Kambhampati, MPH1,4; Shua J. Chai, MD1,5; Arthur Reingold, MD5,6; Isaac Armistead, MD7; Breanna Kawasaki, MPH8; James Meek, MPH9; Kimberly Yousey-Hindes, MPH9; Evan J. Anderson, MD10,11; Kyle P. Openo, DrPH11; Andy Weigel, MSW12; Patricia Ryan, MSc13; Maya L. Monroe, MPH13; Kimberly Fox, MPH14; Sue Kim, MPH14; Ruth Lynfield, MD15; Erica Bye, MPH15; Sarah Shrum Davis, MPH16; Chad Smelser, MD17; Grant Barney, MPH18; Nancy L. Spina, MPH18; Nancy M. Bennett, MD19; Christina B. Felsen, MPH19; Laurie M. Billing, MPH20; Jessica Shiltz, MPH20; Melissa Sutton, MD21; Nicole West, MPH21; H. Keipp Talbot, MD22; William Schaffner, MD22; Ilene Risk, MPA23; Andrea Price23; Lynnette Brammer, MPH1; Alicia M. Fry, MD1,2; Aron J. Since June 18, a discharge diagnosis of multisystem inflammatory syndrome in children (MIS-C) has been systematically collected**; overall, nine (10.8%) of 83 children with completed chart reviews for whom information about MIS-C was systematically collected received a diagnosis of MIS-C. Trained surveillance officers perform medical chart abstractions for all identified cases. Laboratory-confirmed COVID-19–associated hospitalizations among residents in a predefined surveillance catchment area who had a positive SARS-CoV-2 molecular test during hospitalization or up to 14 days before admission are included in surveillance. CDC is not responsible for Section 508 compliance (accessibility) on other federal or private website. † Counties included in COVID-NET surveillance: California (Alameda, Contra Costa, and San Francisco counties); Colorado (Adams, Arapahoe, Denver, Douglas, and Jefferson counties); Connecticut (New Haven and Middlesex counties); Georgia (Clayton, Cobb, DeKalb, Douglas, Fulton, Gwinnett, Newton, and Rockdale counties); Iowa (one county represented); Maryland (Allegany, Anne Arundel, Baltimore, Baltimore City, Calvert, Caroline, Carroll, Cecil, Charles, Dorchester, Frederick, Garrett, Harford, Howard, Kent, Montgomery, Prince George’s, Queen Anne’s, St. Mary’s, Somerset, Talbot, Washington, Wicomico, and Worcester counties); Michigan (Clinton, Eaton, Genesee, Ingham, and Washtenaw counties); Minnesota (Anoka, Carver, Dakota, Hennepin, Ramsey, Scott, and Washington counties); New Mexico (Bernalillo, Chaves, Dona Ana, Grant, Luna, San Juan, and Santa Fe counties); New York (Albany, Columbia, Genesee, Greene, Livingston, Monroe, Montgomery, Ontario, Orleans, Rensselaer, Saratoga, Schenectady, Schoharie, Wayne, and Yates counties); Ohio (Delaware, Fairfield, Franklin, Hocking, Licking, Madison, Morrow, Perry, Pickaway, and Union counties); Oregon (Clackamas, Multnomah, and Washington counties); Tennessee (Cheatham, Davidson, Dickson, Robertson, Rutherford, Sumner, Williamson, and Wilson counties); and Utah (Salt Lake County). NERVTAG also cited a subsequent independent case-control analysis of community testing data linked to death data by Exeter University, which found that the mortality hazard ratio for VOC infected people, versus non-VOC, was 1.91 (1.35 to 2.71). Using a multisite, geographically diverse network, this report found that children with SARS-CoV-2 infection can have severe illness requiring hospitalization and intensive care. As data are received each week, previous case counts and rates are updated accordingly. First, laboratory confirmation is dependent on clinician-ordered SARS-CoV-2 molecular testing. ††† Since June 18, a discharge diagnosis of multisystem inflammatory syndrome in children (MIS-C) was systematically collected through COVID-NET. Similarly, a recent study from the Baltimore-District of Columbia region found a higher prevalence of SARS-CoV-2 infection in the Hispanic community compared with that in other racial and ethnic communities (4). MMWR Morb Mortal Wkly Rep 2020;69:458–64. of pages found at these sites. At a Science Media Centre briefing on 25 January Peter Horby, professor of emerging infectious diseases at the University of Oxford and chair of NERVTAG, said, “What the analysis so far shows is that the rates of death when you link community testing to death is higher in those with the B.1.1.7 variant than matched people with the other virus variant. Sachedina N, Donaldson LJ. But for those in their 40s it goes from around 1 in 500 to 1.3 in 500, and for those in their 20s from 1 in 3000 to 1.3 in 3000, a trivial increase.”. NERVTAG noted that the absolute risk of death per infection “remains low.”, Commenting on the data, David Spiegelhalter, chair of the Winton Centre for Risk and Evidence Communication at the University of Cambridge, said, “The baseline risks go up steeply with age, so for those in their 80s the new variant would take the average mortality risk from 8% to around 10% and for those in 90s from around 20% to 27%—a massive impact. Questions or messages regarding errors in formatting should be addressed to URL addresses listed in MMWR were current as of Evan Anderson reports personal fees from AbbVie, Pfizer and Sanofi Pasteur, and grants from MedImmune, Regeneron, PaxVax, Pfizer, GSK, Merck, Novavax, Sanofi Pasteur, Micron, and Janssen, outside the submitted work. Children can develop severe COVID-19 illness; during the surveillance period, one in three children were admitted to the ICU. provided as a service to MMWR readers and do not constitute or imply What are the implications for public health practice? Unpublished analysis. References to non-CDC sites on the Internet are ** MIS-C is a hyperinflammatory condition that can affect multiple organs in a child who has a current or recent infection with SARS-CoV-2. No other potential conflicts of interest were disclosed. Overall weekly hospitalization rates among children increased steadily during the surveillance period (from 0.1 to 0.4 per 100,000, with a weekly high of 0.7 per 100,000; trend test, p<0.001) (Figure 1). In a briefing paper published on 22 January the government’s New and Emerging Respiratory Virus Threats Advisory Group (NERVTAG) highlighted several preliminary analyses showing a possible increase in the severity of disease associated with the new variant of concern … J Pediatr 2020;223:14–19.e2. Finally, COVID-NET did not systematically collect information on MIS-C until June 18. Phase 3 Trial Shows REGEN-COV™ (casirivimab with imdevimab) Antibody Cocktail Reduced Hospitalization or Death by 70% in Non-hospitalized COVID-19 Patients A higher proportion of included children were aged <6 months, and two sites contributed more than half of cases; however, compared with other single-center or state-based studies, COVID-NET is more geographically and racially diverse (2). Hospitalization Rates and Characteristics of Children Aged <18 Years Hospitalized with Laboratory-Confirmed COVID-19 — COVID-NET, 14 States, March 1–July 25, 2020. All non-Hispanic American Indian/Alaska Native hospitalized children were aged 5–17 years. A medical chart review was completed for 208 (36.1%) children. He J, Guo Y, Mao R, Zhang J. Based on these data, the cumulative COVID-19-associated hospitalization rate among children aged <18 years during March 1–July 25, 2020, was 8.0 per 100,000 population, with the highest rate among children aged <2 years (24.8). NERVTAG paper on COVID-19 variant of concern B.1.1.7: paper from the New and Emerging Respiratory Virus Threats Advisory Group (NERVTAG) on new coronavirus (COVID-19) variant B.1.1.7. Docherty A, Harrison E, Semple C. 2021. The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. ¶¶ Two hospitalized children received extracorporeal membrane oxygenation (1 each aged <2 years and 5–17 years). § Counties included in COVID-NET surveillance: California (Alameda, Contra Costa, and San Francisco counties); Colorado (Adams, Arapahoe, Denver, Douglas, and Jefferson counties); Connecticut (New Haven and Middlesex counties); Georgia (Clayton, Cobb, DeKalb, Douglas, Fulton, Gwinnett, Newton, and Rockdale counties); Iowa (one county represented); Maryland (Allegany, Anne Arundel, Baltimore, Baltimore City, Calvert, Caroline, Carroll, Cecil, Charles, Dorchester, Frederick, Garrett, Harford, Howard, Kent, Montgomery, Prince George’s, Queen Anne’s, St. Mary’s, Somerset, Talbot, Washington, Wicomico, and Worcester counties); Michigan (Clinton, Eaton, Genesee, Ingham, and Washtenaw counties); Minnesota (Anoka, Carver, Dakota, Hennepin, Ramsey, Scott, and Washington counties); New Mexico (Bernalillo, Chaves, Dona Ana, Grant, Luna, San Juan, and Santa Fe counties); New York (Albany, Columbia, Genesee, Greene, Livingston, Monroe, Montgomery, Ontario, Orleans, Rensselaer, Saratoga, Schenectady, Schoharie, Wayne, and Yates counties); Ohio (Delaware, Fairfield, Franklin, Hocking, Licking, Madison, Morrow, Perry, Pickaway, and Union counties); Oregon (Clackamas, Multnomah, and Washington counties); Tennessee (Cheatham, Davidson, Dickson, Robertson, Rutherford, Sumner, Williamson, and Wilson counties); and Utah (Salt Lake County). . But . Based on these data, the cumulative COVID-19-associated hospitalization rate among children aged <18 years during March 1–July 25, 2020, was 8.0 per 100,000 population, with the highest rate among children aged <2 years (24.8). Suggested citation for this article: Kim L, Whitaker M, O’Halloran A, et al. COVID-19 cases are now rising at a pretty alarming rate throughout Michigan and especially in southeast Michigan, and we at Beaumont Health are pretty concerned about the … Although hospitalization rates were lower for Hispanic persons than for black and white persons, hospitalized Hispanic patients were more likely to be younger (aged <44 years) (4). Risk factors for intensive care unit admission and in-hospital mortality among hospitalized adults identified through the U.S. coronavirus disease 2019 (COVID-19)-associated hospitalization surveillance network (COVID-NET). Eli Lilly's combination antibody drug cuts the risk of COVID-19 hospitalization and death by 87%, study finds . LSHTM. This conversion might result in character translation or format errors in the HTML version. Reported signs and symptoms upon hospital admission differed by age: fever or chills were the most common sign and symptom overall (54%) and were most prevalent among children aged <2 years (74.6%). Trend test overall (<18 years): p-value <0.001. endorsement of these organizations or their programs by CDC or the U.S. Although the cumulative COVID-19–associated hospitalization rate among children is low compared with that among adults, weekly hospitalization rates in children increased during the surveillance period. During March 1–July 25, 576 children hospitalized with COVID-19 were reported to COVID-NET. Under an EUA issued by the FDA, REGEN-COV is currently available in the U.S. to treat mild-to-moderate COVID-19 in adults, as well as in pediatric patients at least 12 years of age and weighing at least 40 kg, who have received positive results of direct SARS-CoV-2 viral testing and are at high risk for progressing to severe COVID-19 and/or hospitalization. All HTML versions of MMWR articles are generated from final proofs through an automated process. † Figure B shows the 3-week moving average of weekly hospitalization rates for children in each age group hospitalized with COVID-19 per 100,000 population. The latest results are an improvement from earlier findings. In the future, COVID-NET plans to have complete, population-based data on hospitalized children. Although the cumulative rate of pediatric COVID-19–associated hospitalization remains low (8.0 per 100,000 population) compared with that among adults (164.5),* weekly rates increased during the surveillance period, and one in three hospitalized children were admitted to the ICU, similar to the proportion among adults. N Engl J Med 2020;383:347–58. On August 7, 2020, this report was posted online as an MMWR Early Release. Use of trade names and commercial sources is for identification only and does not imply endorsement by the U.S. Department of § Data are preliminary, and case counts and rates for recent hospital admissions are subject to lag. Continued surveillance will allow for further characterization of the burden and outcomes of COVID-19–associated hospitalizations among children. Copyright © 2021 BMJ Publishing Group Ltd 京ICP备15042040号-3, Covid-19: New UK variant may be linked to increased death rate, early data indicate, https://www.gov.uk/government/publications/nervtag-paper-on-covid-19-variant-of-concern-b117, https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/955239/NERVTAG_paper_on_variant_of_concern__VOC__B.1.1.7.pdf, TDM Consulting: Locum Consultant Psychiatrist x 4, Great Ormond Street Hospital for Children NHS Trust: Medical Director, Somerset NHS Foundation Trust: Oral & Maxillofacial Surgery, GenesisCare: Advanced Radiotherapy Fellowship, Women’s, children’s & adolescents’ health. Results from a Phase 3 U.S. trial of the Oxford-AstraZeneca COVID-19 vaccine has shown that the two-dose shot reduced symptomatic disease by 79 per cent, said a press release Monday, and reduced severe disease and hospitalization by 100 per cent. the date of publication. Among 208 (36.1%) hospitalized children with complete medical chart reviews, 69 (33.2%) were admitted to an intensive care unit (ICU); 12 of 207 (5.8%) required invasive mechanical ventilation, and one patient died during hospitalization. Similar to the general population, children should be encouraged to wash their hands often and continue social distancing, and children aged ≥2 years should wear a mask when around persons outside of their families to reduce the risk for SARS-CoV-2 infection and transmission to others. Continued tracking of SARS-CoV-2 infections among children is important to characterize morbidity and mortality. During March 21–July 25, weekly hospitalization rates steadily increased among children (from 0.1 to 0.4 per 100,000, with a weekly high of 0.7 per 100,000). Infants aged <3 months accounted for 18.8% of all children hospitalized with COVID-19 (Table). Continued monitoring of hospitalizations, ICU admissions, and mortality among children is important to understand potential risk factors for severe outcomes. Zachariah P, Johnson CL, Halabi KC, et al. Abbreviation: COVID-NET = Coronavirus Disease 2019–Associated Hospitalization Surveillance Network. This question is for testing whether or not you are a human visitor and to prevent automated spam submissions. Views equals page views plus PDF downloads. Davies N, Diaz-Ordaz K, Keogh R. 2021. ¶ Data collected only on children aged <2 years. Second, hospitalization rates by age group and race/ethnicity are preliminary and might change as additional cases are identified during the surveillance period. . Relative fatality hazard in Pillar 2 tested individuals with VOC. Lancet 2010;376:1846–52. Hales CM, Carroll MD, Fryar CD, Ogden CL. Analysis of pediatric COVID-19 hospitalization data from 14 states found that although the cumulative rate of COVID-19–associated hospitalization among children (8.0 per 100,000 population) is low compared with that in adults (164.5), one in three hospitalized children was admitted to an intensive care unit. 1 min read. COVID-19 investigational treatments were only administered to 12 (5.8%) children, all aged 5–17 years; nine received remdesivir. Among 526 (91.3%) children for whom race and ethnicity information were reported, 241 (45.8%) were Hispanic, 156 (29.7%) were black, 74 (14.1%) were white; 24 (4.6%) were non-Hispanic Asian or Pacific Islander; and four (0.8%) were non-Hispanic American Indian/Alaska Native. mmwrq@cdc.gov. None received renal replacement therapy. J Pediatric Infect Dis Soc 2019;8:539–49. Ongoing monitoring of hospitalization rates, clinical characteristics, ICU admission, and outcomes in the pediatric population is important to further characterize the morbidity and mortality of COVID-19 in children. Improved understanding of the social determinants of health is needed to inform and reduce disparities as evidenced by pediatric COVID-19-associated hospitalization rates. LONDON — U.K. food bank rose by a third during the past 12 months as the COVID-19 pandemic left more people without the money to buy basic necessities, a charity that distributes food said Thursday. The London School’s analysis was based on 2583 deaths among 1.2 million tested individuals; 384 deaths were among people with SGTF. Results from a Phase 3 U.S. trial of the Oxford-AstraZeneca COVID-19 vaccine has shown that the two-dose shot reduced symptomatic disease by 79 per cent, said a press release Monday, and reduced severe disease and hospitalization by 100 per cent. §§ Not given for human immunodeficiency virus infection. † Counties in COVID-NET surveillance: California (Alameda, Contra Costa, and San Francisco counties); Colorado (Adams, Arapahoe, Denver, Douglas, and Jefferson counties); Connecticut (New Haven and Middlesex counties); Georgia (Clayton, Cobb, DeKalb, Douglas, Fulton, Gwinnett, Newton, and Rockdale counties); Iowa (one county represented); Maryland (Allegany, Anne Arundel, Baltimore, Baltimore City, Calvert, Caroline, Carroll, Cecil, Charles, Dorchester, Frederick, Garrett, Harford, Howard, Kent, Montgomery, Prince George’s, Queen Anne’s, St. Mary’s, Somerset, Talbot, Washington, Wicomico, and Worcester counties); Michigan (Clinton, Eaton, Genesee, Ingham, and Washtenaw counties); Minnesota (Anoka, Carver, Dakota, Hennepin, Ramsey, Scott, and Washington counties); New Mexico (Bernalillo, Chaves, Dona Ana, Grant, Luna, San Juan, and Santa Fe counties); New York (Albany, Columbia, Genesee, Greene, Livingston, Monroe, Montgomery, Ontario, Orleans, Rensselaer, Saratoga, Schenectady, Schoharie, Wayne, and Yates counties); Ohio (Delaware, Fairfield, Franklin, Hocking, Licking, Madison, Morrow, Perry, Pickaway, and Union counties); Oregon (Clackamas, Multnomah, and Washington counties); Tennessee (Cheatham, Davidson, Dickson, Robertson, Rutherford, Sumner, Williamson, and Wilson counties); and Utah (Salt Lake County). start highlight§ Obesity was defined as body mass index (kg/m2) ≥95th percentile for age and sex based on CDC growth charts among children aged ≥2 years; this was not evaluated for children <2 years.end highlight Clinical characteristics and outcomes of hospitalized and critically ill children and adolescents with coronavirus disease 2019 (COVID-19) at a tertiary care medical center in New York City. This suggests that the presence of underlying conditions place children at higher risk for COVID-19-associated hospitalizations and that observed disparities might in part be related to the higher prevalence of underlying conditions among hospitalized Hispanic and black children compared with those among white children. J Med Virol 2020;jmv.26326. The percentage of ICU admission was similar among children (33.2%) and adults (32.0%) reported to COVID-NET; however, invasive mechanical ventilation was required less frequently in children (5.8%) than in adults (18.6%) (3). Since March 1, 2020, COVID-NET has identified 576 pediatric COVID-19–associated hospitalizations. Among 222 (38.5%) of 576 children with information on underlying medical conditions, 94 (42.3%) had one or more underlying conditions (Table). CDC is not responsible for the content Access provided by India:BMJ-PG Sponsored. Reinforcement of prevention efforts is essential in congregate settings that serve children, including childcare centers and schools. Hispanic and black children had the highest rates of COVID-19–associated hospitalization. The findings in this report are subject to at least five limitations. The median patient age was 8 years (interquartile range [IQR] = 9 months–15 years), and 292 (50.7%) were males. Clinical data on underlying conditions and symptoms at admission are presented through March 30; hospitalization rates are updated weekly and, therefore, are presented through March 28 (epidemiologic week 13). Rates likely are underestimates; cases can be missed because of test availability, test performance, and provider or facility testing practices. † Analyses were conducted on all available data; however, for hospitalization length of stay, radiology findings, treatments, ICU admission, interventions, new clinical diagnoses, and outcome, only cases with a complete medical chart review and a discharge disposition (i.e. Among 14 children with chest computed tomography results available, ground-glass opacities (a nonspecific sign indicating infection or alveolar disease) was reported in 10. During March 1–July 25, 2020, 576 pediatric COVID-19 cases were reported to the COVID-19–Associated Hospitalization Surveillance Network (COVID-NET), a population-based surveillance system that collects data on laboratory-confirmed COVID-19–associated hospitalizations in 14 states (2,3). Chao JY, Derespina KR, Herold BC, et al. MMWR Morb Mortal Wkly Rep 2020;69:1081–1088. Health and Human Services. Department of Health and Human Services. there is quite a lot of evidence, and the effect is not small.”. First to Demonstrate Clinical Efficacy Against COVID-19 and Both UK and South Africa Variants. During the 2009 influenza A H1N1 pandemic, pediatric mortality rates also were higher among underrepresented ethnic groups in a study from England (5). This report found the highest rates of COVID-19-associated hospitalization among Hispanic children. Most reported cases of coronavirus disease 2019 (COVID-19) in children aged <18 years appear to be asymptomatic or mild (1). We do not capture any email address. Martinez DA, Hinson JS, Klein EY, et al. Approximately 60% of pediatric hospitalizations reported to COVID-NET have not had a chart review, and this sample might be biased. 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